Research material

In stock ≥99.0%

Semaglutide

Synthetic 31-residue GLP-1 analogue studied as a long-acting GLP-1 receptor agonist in receptor-pharmacology models.


Specification

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For research purposes only — not for human consumption.

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Material specifications

Identity & handling.

Catalog #
semaglutide
CAS #
910463-68-2
Purity
≥99.0%
Molecular weight
4113.58 Da
SEQUENCE
H-Aib-EGTFTSDVSSYLEGQAAK*EFIAWLVRGRG-OH (K* = lipidated Lys20)
Molecular formula
C187H291N45O59
Synonyms
NN9535
Storage
−20°C lyophilized
Appearance
White lyophilized powder
Research area
Weight & Metabolic Research
Common strengths
10 MG, 20 MG, 30 MG

Analytical preview

Published evidence.

Semaglutide is a synthetic GLP-1 analogue with an Aib substitution at position 2 and a C18 fatty-diacid side chain. It is studied in cell-based and preclinical models as a GLP-1 receptor agonist; the side chain promotes albumin binding and extends its half-life in those models.

HPLC / 214 NM / ANALYTICAL PREVIEW

Citations

Product citations

  • Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide Journal of Medicinal Chemistry · 2015

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